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An in vitro fertilization technique for overcoming infertility due to oligospermia or azoospermia involving sperm microinjection (SMI), in which one or more sperm are injected through the zona pellucida, across the perivitelline space, through the vitelline membrane (the egg cell’s membrane), and into the substance (or cytoplasm) of the egg itself. Has completely replaced subzonal sperm insertion (SUZI)
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