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Originally a botanical term meaning asexual reproduction, or reproduction by "budding" rather than by genetic recombination involving an egg and a sperm. Animals can be cloned either by splitting an embryo during cleavage (nature does this in producing monozygotic twinning) or by inserting an adult cell nucleus into a suitably primed secondary oocyte, a process called somatic cell nuclear transfer (and generally still very inefficient, resulting in a new developing embryo in at most a few percent of attempts). See also therapeutic cloning and reproductive cloning
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